Mega-Cap & Large-Cap Stocks See Big Moves: UnitedHealth Rallies, Nvidia Faces Setback

Monday trading session witnessed some major shifts in stocks, particularly among mega-cap and large-cap companies, with a blend of company-specific news and broader market factors shaping investor sentiment. As the market reacts to various developments, these stocks are seeing notable intra-day movements.

Mega-Cap Stock Movements: UnitedHealth Shines While Tech Giants Struggle

Among the mega-cap stocks (companies with market capitalizations over $200 billion), UnitedHealth Group (UNH) emerged as a standout performer, gaining 4.36%. The health insurer’s rally is attributed to positive market sentiment, boosted by strong fundamentals and solid investor confidence in the sector.

On the flip side, Apple Inc. (AAPL) saw a 2.76% decline, reflecting broader market concerns about tech stock performance amid rising inflation and potential interest rate hikes. Similarly, Nvidia Corp. (NVDA) faced a significant drop of 3.77%, as reports surfaced regarding glitches with their AI chip racks, leading to delays for top customers. These setbacks have raised concerns about Nvidia’s growth prospects in the competitive AI space, despite its dominant position.

Other notable losers in the mega-cap category included Facebook Inc. (META), which fell 2.48%, and Thermo Fisher Scientific (TMO), which posted a modest 2.39% gain.

Large-Cap Stock Movers: Intracellular Therapies Soars While Edison International Struggles

In the large-cap category (market cap between $10 billion and $200 billion), Intracellular Therapies (ITCI) saw a staggering 34.48% rise, fueled by reports of potential acquisition talks with Johnson & Johnson (JNJ), according to Bloomberg. This development has sparked investor optimism about the company’s future prospects under the pharmaceutical giant’s ownership.

Meanwhile, Humana Inc. (HUM) posted a solid 6.59% gain, further strengthening its position in the healthcare sector. However, Edison International (EIX) took a hit, dropping 9.95% after the company provided an update on the ongoing Southern California wildfires and power outages, which have been affecting its operations.

Other large-cap stocks showing weakness included Vector Acquisition (RKLB), which fell 9.33%, and Constellation Energy Group (CEG), which lost 7.22%.

Mid-Cap Stocks: Rigetti Computing Faces Major Decline

Among mid-cap stocks (market cap between $2 billion and $10 billion), Rigetti Computing (RGTI) suffered a significant loss of 23.4%. The company’s struggles are compounded by market concerns over its position in the rapidly evolving quantum computing industry. Other notable decliners in this category included Abercrombie & Fitch (ANF), down 18.15%, and SpringWorks Therapeutics (SWTX), which saw a 15.91% drop after it provided preliminary financial results at the 43rd Annual J.P. Morgan Healthcare Conference.

Additionally, TransMedics Group Inc. (TMDX) faced a 12.64% decline after responding to a short-seller report that accused the company of misleading claims.

Small-Cap Stocks: Sage Therapeutics Stands Out

In the small-cap sector (market cap between $300 million and $2 billion), Sage Therapeutics (SAGE) made headlines with a massive 35.86% surge. The company’s announcement at the J.P. Morgan Healthcare Conference about its strategic focus for 2025 sparked investor optimism. In contrast, AirSculpt Technologies (AIRS) saw its stock plummet 29.77%, and Establishment Labs Holdings Inc. (ESTA) dropped 26.33%, after management changes and revised fiscal guidance.

Fluidigm Corp. (LAB) posted a solid 21.78% gain, following preliminary revenue updates that exceeded market expectations.

A Day of Big Moves Across Market Capitalizations

Monday’s trading session has provided a mix of opportunities and challenges for investors, with notable movements seen across mega-cap, large-cap, mid-cap, and small-cap stocks. From strong gains in UnitedHealth and Sage Therapeutics to significant setbacks for Nvidia and Edison International, today’s market actions reflect the varied factors driving investor sentiment across different sectors. As the year unfolds, these developments are shaping the broader market landscape.